Repeated USMLE Questions Step 1 -151

A 2-year-old boy originally from Egypt is diagnosed with anemia after he took antibiotics for the treatment of otitis media. He has two brothers and one sister. One of his brothers was diagnosed with anemia when he was two years old. His parents were given a list of food and drugs that could be associated with this type of anemia. What is the mode of inheritance of this condition?

A-Autosomal dominant

B-Autosomal recessive

C-X-linked recessive

D-Mitochondrial

E-Multifactorial






Answer

This is a case of glucose-6-phosphate dehydrogenase (G6PD) deficiency which is common in Africa and Mediterranean region. It is x-linked recessive disorder.

The correct answer is C