Repeated USMLE Questions Step 1- 171

A 38 year-old woman visits her physician complaining of palpitations, insomnia and heat intolerance. On examination, her pulse is 110/min, blood pressure is 130/80 and her temperature is 99.1 F. She has fine tremors and bulging of her eyes.

What is the most likely laboratory finding to confirm her diagnosis?

A- High serum cortisol

B- High serum thyroid stimulating hormone

C- High serum prolactin

D- Presence of thyroid-stimulating hormone receptor antibodies

E- Presence of antinuclear antibodies

Answer:







This is a typical presentation of Graves’ disease. The only laboratory test of the listed options that confirms this diagnosis is the presence of thyroid stimulating hormone receptor antibodies.

The correct answer is D